Pseudomonas aeruginosa is an opportunistic pathogen and causes infections in the lungs of cystic fibrosis patients. Motility and biofilm formation are large contributing factors to the ability of P. aeruginosa to cause infection, and these processes have been found to be modulated by multiple biological molecules including rhamnolipid, a biosurfactant produced by RhlA, WspA, a protein predicted to have a role in surface sensing, and MotB and MotD, proteins that contribute to the flagella stator complex. In this work, we evaluated the impact of the deletion genes encoding for expression of these factors on the pathogenicity of P. aeruginosa.
Hicks, Makayla and McGrane, Regina, "Evaluating pathogenicity of Pseudomonas aeruginosa by manipulating genes associated with motility and biofilm formation" (2021). Student Research. 2.